B6;129P2-Dp(17Abcg1-Cbs)1Yah/Orl
| Status | Available to order |
| EMMA ID | EM:01987 |
| International strain name | B6;129P2-Dp(17Abcg1-Cbs)1Yah/Orl |
| Alternative name | Dup(Abcg1-U2af1) n°138/+ |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Dp(17Abcg1-Cbs)1Yah, |
| Gene/Transgene symbol | Dp(17Abcg1-Cbs)1Yah |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
| Genetic information | Duplication of the region between Abcg1-U2af1 genes on the MMU17. |
| Phenotypic information | No visible phenotype, fertility is normal. |
| Breeding history | 2 backcrosses on C57BL/6. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI allele-associated human disease models
Literature references
- A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.;Pereira Patricia Lopes, Magnol Laetitia, Sahún Ignasi, Brault Véronique, Duchon Arnaud, Prandini Paola, Gruart Agnès, Bizot Jean-Charles, Chadefaux-Vekemans Bernadette, Deutsch Samuel, Trovero Fabrice, Delgado-García José María, Antonarakis Stylianos E, Dierssen Mara, Herault Yann, ;2009;Human molecular genetics;18;4756-69; 19783846
- Rodent models in Down syndrome research: impact and future opportunities.;Herault Yann, Delabar Jean M, Fisher Elizabeth M C, Tybulewicz Victor L J, Yu Eugene, Brault Veronique, ;2017;Disease models & mechanisms;10;1165-1186; 28993310