129-Ightm3.1Cog/Orl
Status | Available to order |
EMMA ID | EM:00212 |
International strain name | 129-Ightm3.1Cog/Orl |
Alternative name | delta hs3b/hs4 |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Ightm3.1Cog, |
Gene/Transgene symbol | Igh |
Information from provider
Provider | Michel Cogne |
Provider affiliation | UMR CNRS 6101, Universite de Limoges |
Genetic information | Deletion of the hs3b and hs4 transcriptional enhancers within the Igh locus, 3 prime-regulatory region. |
Phenotypic information | Immunoglobulin IgG2b, IgG2a, IgG3, IgE and IgA class switching defects. |
References |
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Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (allele matching)
Literature references
- Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination.;Pinaud E, Khamlichi A A, Le Morvan C, Drouet M, Nalesso V, Le Bert M, Cogné M, ;2001;Immunity;15;187-99; 11520455
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