B6.FVB-Tg(Aqp2-icre)1Gsc/Ieg
Status | Available to order |
EMMA ID | EM:02127 |
International strain name | B6.FVB-Tg(Aqp2-icre)1Gsc/Ieg |
Alternative name | AQP2 Cre 2-copy line |
Strain type | Transgenic Strains |
Allele/Transgene symbol | Tg(Aqp2-icre)1Gsc, |
Gene/Transgene symbol | Tg(Aqp2-icre)1Gsc |
Information from provider
Provider | Günther Schütz |
Provider affiliation | Molecular Biology of the Cell I, German Cancer Research Center |
Genetic information | An open reading frame encoding the cre recombinase was introduced by homologous recombination in bacteria at the start codon of the Aqp2 gene on a PAC containing a 125 kb upstream region and a 31 kb downstream region of the mouse Aqp2 gene. |
Phenotypic information | None. |
References |
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Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Literature references
- Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor.;Ronzaud Caroline, Loffing Johannes, Bleich Markus, Gretz Norbert, Gröne Hermann-Josef, Schütz Günther, Berger Stefan, ;2007;Journal of the American Society of Nephrology : JASN;18;1679-87; 17475815
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