TFH/H

Status

Available to order

EMMA IDEM:02207
International strain nameTFH/H
Alternative nameTFH/H
Strain typeSpontaneous
Allele/Transgene symbolItpr3tf,
Gene/Transgene symbolItpr3

Information from provider

ProviderMary Lyon
Provider affiliationMRC Mammalian Genetics Unit
Genetic informationHomozygous for tufted (Itpr3tf) with forced heterozygosis for T allele.
Phenotypic informationMice heterozygous for TFH/H have short tails. Mice homozygous for this mutation are non-viable.
References
  • Transmission ratio distortion in mouse t-haplotypes is due to multiple distorter genes acting on a responder locus.;Lyon M F, ;1984;Cell;37;621-8; 6722884

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI allele-associated human disease models

MGI phenotypes (allele matching)
  • abnormal cerebral cortex morphology / MGI
  • increased body weight / MGI
  • abnormal social investigation / MGI
  • decreased anxiety-related response / MGI
  • increased grooming behavior / MGI
  • abnormal vocalization / MGI
  • absent corpus callosum / MGI
  • abnormal brain commissure morphology / MGI
  • increased growth rate / MGI
  • impaired social transmission of food preference / MGI
  • abnormal locomotor activation / MGI
  • decreased hippocampal commissure size / MGI
  • decreased anterior commissure size / MGI
  • abnormal neocortex morphology / MGI
  • abnormal allogrooming behavior / MGI
  • excessive vocalization / MGI
  • abnormal coat/ hair morphology / MGI
  • sparse hair / MGI
  • abnormal hair cycle / MGI
  • abnormal liquid preference / MGI
  • abnormal gustatory system physiology / MGI
  • abnormal hair growth / MGI
  • increased fluid intake / MGI
  • low sweet preference / MGI

Literature references

  • Transmission ratio distortion in mouse t-haplotypes is due to multiple distorter genes acting on a responder locus.;Lyon M F, ;1984;Cell;37;621-8; 6722884

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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