- abnormal cerebral cortex morphology / MGI
- increased body weight / MGI
- abnormal social investigation / MGI
- decreased anxiety-related response / MGI
- increased grooming behavior / MGI
- abnormal vocalization / MGI
- absent corpus callosum / MGI
- abnormal brain commissure morphology / MGI
- increased growth rate / MGI
- impaired social transmission of food preference / MGI
- abnormal locomotor activation / MGI
- decreased hippocampal commissure size / MGI
- decreased anterior commissure size / MGI
- abnormal neocortex morphology / MGI
- abnormal allogrooming behavior / MGI
- excessive vocalization / MGI
- abnormal coat/ hair morphology / MGI
- sparse hair / MGI
- abnormal hair cycle / MGI
- abnormal liquid preference / MGI
- abnormal gustatory system physiology / MGI
- abnormal hair growth / MGI
- increased fluid intake / MGI
- low sweet preference / MGI
TFH/H
Status | Available to order |
EMMA ID | EM:02207 |
International strain name | TFH/H |
Alternative name | TFH/H |
Strain type | Spontaneous |
Allele/Transgene symbol | Itpr3tf, |
Gene/Transgene symbol | Itpr3 |
Information from provider
Provider | Mary Lyon |
Provider affiliation | MRC Mammalian Genetics Unit |
Genetic information | Homozygous for tufted (Itpr3tf) with forced heterozygosis for T allele. |
Phenotypic information | Mice heterozygous for TFH/H have short tails. Mice homozygous for this mutation are non-viable. |
References |
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Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
MGI phenotypes (allele matching)
Literature references
- Transmission ratio distortion in mouse t-haplotypes is due to multiple distorter genes acting on a responder locus.;Lyon M F, ;1984;Cell;37;621-8; 6722884
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