B6D2-Tg(Scgb1a1-cre)1Tauc/Orl

Status	Available to order
EMMA ID	EM:02464
International strain name	B6D2-Tg(Scgb1a1-cre)1Tauc/Orl
Alternative name	gL4-CCSP-Cre
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Scgb1a1-cre)1Tauc,
Gene/Transgene symbol	Tg(Scgb1a1-cre)1Tauc

Information from provider

Provider	Michel Tauc
Provider affiliation	UMR-CNRS 6548 Laboratoire de Physiologie Cellulaire et Moléculaire
Genetic information	Specific expression of Cre recombinase in Clara cells. The linear purified transgene was injected into the pronuclei of fertilized oocytes of B6D2F1 animals, and the injected embryos were transferred into pseudopregnant mice according to standard techniques.
Phenotypic information	Specific expression of Cre recombinase in Clara cells.
Breeding history	Founder mice were backcrossed with B6D2 F1 animals to generate transgenic lines.
References	In vivo Cre/loxP mediated recombination in mouse Clara cells.;Bertin Guillaume, Poujeol Chantal, Rubera Isabelle, Poujeol Philippe, Tauc Michel, ;2005;Transgenic research;14;645-54; 16245155
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Institut de Transgenose, INTRAGENE, Orléans, France
Animals used for archiving	heterozygous DBA/2 x C57BL/6, wild-type C57BL/6J
Stage of embryos	2-cell

Literature references

In vivo Cre/loxP mediated recombination in mouse Clara cells.;Bertin Guillaume, Poujeol Chantal, Rubera Isabelle, Poujeol Philippe, Tauc Michel, ;2005;Transgenic research;14;645-54; 16245155
A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection.;Maelfait Jonathan, Roose Kenny, Vereecke Lars, Mc Guire Conor, Sze Mozes, Schuijs Martijn J, Willart Monique, Ibañez Lorena Itati, Hammad Hamida, Lambrecht Bart N, Beyaert Rudi, Saelens Xavier, van Loo Geert, ;2016;PLoS pathogens;12;e1005410; 26815999
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells.;Schuijs Martijn J, Willart Monique A, Vergote Karl, Gras Delphine, Deswarte Kim, Ege Markus J, Madeira Filipe Branco, Beyaert Rudi, van Loo Geert, Bracher Franz, von Mutius Erika, Chanez Pascal, Lambrecht Bart N, Hammad Hamida, ;2015;Science (New York, N.Y.);349;1106-10; 26339029

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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