- hearing/vestibular/ear phenotype / MGI
- organ of Corti degeneration / MGI
- abnormal stria vascularis morphology / MGI
- abnormal hearing physiology / MGI
- deafness / MGI
- abnormal motor capabilities/coordination/movement / MGI
- abnormal ear morphology / MGI
- cochlear ganglion degeneration / MGI
- abnormal otolith morphology / MGI
- abnormal tectorial membrane morphology / MGI
- abnormal scala media morphology / MGI
- nervous system phenotype / MGI
- vestibular saccular macula degeneration / MGI
- Deiters cell degeneration / MGI
- head tossing / MGI
STOCK Tmc1dn/WtsiH
Status | Available to order |
EMMA ID | EM:00386 |
International strain name | STOCK Tmc1dn/WtsiH |
Alternative name | Dn |
Strain type | Spontaneous |
Allele/Transgene symbol | Tmc1dn, |
Gene/Transgene symbol | Tmc1 |
Information from provider
Provider | Karen Steel |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | The mutation is a 1656 bp deletion including exon 14 and flanking intronic sequences. |
Phenotypic information | Mice homozygous for this mutation are deaf and show no Preyer reflex. Heterozygotes and wild-types are indistinguishable. |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
MGI phenotypes (allele matching)
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).