- abnormal eye morphology / MGI
- mydriasis / MGI
- abnormal sternum morphology / MGI
- abnormal xiphoid process morphology / MGI
- double outlet right ventricle / MGI
- irregularly shaped pupil / MGI
- abnormal palatal shelf fusion at midline / MGI
- ventricular septal defect / MGI
- prenatal lethality, complete penetrance / MGI
C3;C-FlnaDilp2/H
Status | Available to order |
EMMA ID | EM:00387 |
International strain name | C3;C-FlnaDilp2/H |
Alternative name | GENA379, Dilp2 (Dilated pupils 2) |
Strain type | Induced Mutant Strains : Chemically-induced |
Allele/Transgene symbol | FlnaDilp2, |
Gene/Transgene symbol | Flna |
Information from provider
Provider | Caroline Thaung |
Provider affiliation | MRC Mammalian Genetics Unit |
Phenotypic information | Mice heterozygous for this mutation have dilated pulpils. Homozygous animals are not generated. |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- X-linked keloid scarring-reduced joint mobility-increased optic cup-to-disc ratio syndrome / Orphanet_482606
- Periventricular nodular heterotopia / Orphanet_98892
- X-linked Ehlers-Danlos syndrome / Orphanet_75497
- Otopalatodigital syndrome type 2 / Orphanet_90652
- Frontometaphyseal dysplasia / Orphanet_1826
- Otopalatodigital syndrome type 1 / Orphanet_90650
- Melnick-Needles syndrome / Orphanet_2484
- Congenital short bowel syndrome / Orphanet_2301
- Neuronal intestinal pseudoobstruction / Orphanet_99811
- FLNA-related X-linked myxomatous valvular dysplasia / Orphanet_555877
- Terminal osseous dysplasia-pigmentary defects syndrome / Orphanet_88630
MGI phenotypes (allele matching)
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