B6.Cg-Tg(Cebpb-rtTA2S*S2)1Bjd/Cnrm
| Status | Available to order |
| EMMA ID | EM:00404 |
| International strain name | B6.Cg-Tg(Cebpb-rtTA2S*S2)1Bjd/Cnrm |
| Alternative name | rTALAP-1 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Cebpb-rtTA2S*S2)1Bjd, |
| Gene/Transgene symbol | Tg(Cebpb-rtTA2S*S2)1Bjd |
Information from provider
| Provider | Hermann Bujard |
| Provider affiliation | Zentrum für Molekulare Biologie Heidelberg- ZMBH |
| Genetic information | Transgenic rTALAP-1 mice contain a transcription unit consisting of the liver-enriched activating protein (LAP or Cebpb) promoter region which extends to nt 2800, and a synthetic gene encoding the rtTA2S-S2 transactivator variant (Urlinger et al., Proc Natl Acad Sci USA ,2000), followed by the beta-globin intron/poly(A) sequence. |
| Phenotypic information | Expression of the rtTA2S-S2 transactivator variant (Urlinger et al., Proc Natl Acad Sci USA, 2000), followed by the beta-globin intron/poly(A) sequence. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Stringent doxycycline dependent control of CRE recombinase in vivo.;Schönig Kai, Schwenk Frieder, Rajewsky Klaus, Bujard Hermann, ;2002;Nucleic acids research;30;e134; 12466566
- Use of the tetracycline system for inducible protein synthesis in the kidney.;Gallagher Anna Rachel, Schönig Kai, Brown Nelson, Bujard Hermann, Witzgall Ralph, ;2003;Journal of the American Society of Nephrology : JASN;14;2042-51; 12874458
- Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity.;Urlinger S, Baron U, Thellmann M, Hasan M T, Bujard H, Hillen W, ;2000;Proceedings of the National Academy of Sciences of the United States of America;97;7963-8; 10859354