STOCK Myo7a3336SB/NihrH
Status | Available to order |
EMMA ID | EM:00427 |
International strain name | STOCK Myo7a3336SB/NihrH |
Alternative name | Myo7a |
Strain type | Induced Mutant Strains : Chemically-induced |
Allele/Transgene symbol | Myo7a3336SB, |
Gene/Transgene symbol | Myo7a |
Information from provider
Provider | Karen Steel |
Provider affiliation | Wellcome Trust Sanger Institute |
Phenotypic information | Mice homozygous for this mutation exhibit almost constant circling behaviour and show no Preyer reflex. Heterozygotes and wild-types are indistinguishable. |
References |
|
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- Usher syndrome type 1 / Orphanet_231169
- Autosomal recessive non-syndromic sensorineural deafness type DFNB / Orphanet_90636
- Usher syndrome type 2 / Orphanet_231178
- Autosomal dominant non-syndromic sensorineural deafness type DFNA / Orphanet_90635
MGI phenotypes (allele matching)
Literature references
- Effects of shaker-1 mutations on myosin-VIIa protein and mRNA expression.;Hasson T, Walsh J, Cable J, Mooseker M S, Brown S D, Steel K P, ;1997;Cell motility and the cytoskeleton;37;127-38; 9186010
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).