B6.Cg-Tg(tetO-Creb*)100Brco/Cnbc

Status

Available to order

EMMA IDEM:04664
International strain nameB6.Cg-Tg(tetO-Creb*)100Brco/Cnbc
Alternative nametetO-ACREB100
Strain typeTransgenic Strains
Allele/Transgene symbolTg(tetO-Creb*)100Brco,
Gene/Transgene symbolTg(tetO-Creb*)100Brco

Information from provider

ProviderAngel Barco
Provider affiliationServicio de Experimentación Animal, Instituto de Neurociencias de Alicante
Genetic informationTetracycline regulated expression of the CREB inhibitor, A-CREB. Transgene intended to be used in bitransgenic lines after crossing with tTA or rtTA expressing mice.
Phenotypic informationAfter crossing with CamKIIa-tTA the bitransgenic line showed striatal specific expression. The addiction related phenotypes are described in Front Behav Neurosci. 2009;3:30.
Breeding historyBackcrossed to C57BL/6J for more than 15 generations.
References
  • Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues.;Sanchis-Segura Carles, Jancic Dragana, Jimenez-Minchan Maria, Barco Angel, ;2009;Frontiers in behavioral neuroscience;3;30; 19826619
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6J, wild-type C57BL/6J
Stage of embryos8-cell

Literature references

  • Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues.;Sanchis-Segura Carles, Jancic Dragana, Jimenez-Minchan Maria, Barco Angel, ;2009;Frontiers in behavioral neuroscience;3;30; 19826619

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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