B6Brd;B6N-Tyrc-Brd Slx4tm1a(EUCOMM)Wtsi/WtsiCnbc
Status | Available to order |
EMMA ID | EM:05091 |
International strain name | B6Brd;B6N-Tyrc-Brd Slx4tm1a(EUCOMM)Wtsi/WtsiCnbc |
Alternative name | EPD0028_7_A08 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Slx4tm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Slx4 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0028_7_A08. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Fanconi anemia / Orphanet_84
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
- decreased leukocyte cell number / MGI
- abnormal cranium morphology / MGI
- enlarged cranium / MGI
- domed cranium / MGI
- abnormal cerebral cortex morphology / MGI
- dilated lateral ventricles / MGI
- abnormal third ventricle morphology / MGI
- obstructive hydrocephaly / MGI
- absent mature ovarian follicles / MGI
- absent corpus luteum / MGI
- abnormal spermatogenesis / MGI
- decreased body weight / MGI
- decreased body size / MGI
- anophthalmia / MGI
- microphthalmia / MGI
- abnormal cornea morphology / MGI
- corneal opacity / MGI
- abnormal pupil morphology / MGI
- abnormal iris morphology / MGI
- absent optic nerve / MGI
- postnatal growth retardation / MGI
- hydroencephaly / MGI
- reduced male fertility / MGI
- reduced female fertility / MGI
- decreased litter size / MGI
- abnormal eye morphology / MGI
- abnormal tooth morphology / MGI
- abnormal lymphopoiesis / MGI
- oligozoospermia / MGI
- abnormal retinal vasculature morphology / MGI
- increased erythrocyte cell number / MGI
- thrombocytopenia / MGI
- nervous system phenotype / MGI
- abnormal eyelid aperture / MGI
- abnormal spine curvature / MGI
- vertebral fusion / MGI
- absent oocytes / MGI
- azoospermia / MGI
- impaired glucose tolerance / MGI
- increased circulating glucose level / MGI
- thin cerebral cortex / MGI
- early cellular replicative senescence / MGI
- abnormal male germ cell apoptosis / MGI
- abnormal primordial germ cell morphology / MGI
- decreased common myeloid progenitor cell number / MGI
- chromosomal instability / MGI
- increased physiological sensitivity to xenobiotic / MGI
- increased sensitivity to induced cell death / MGI
- increased caudal vertebrae number / MGI
- perinatal lethality, incomplete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI
- abnormal eye size / MGI
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