- decreased bone mineral density / IMPC
- abnormal tibia morphology / IMPC
- decreased body length / IMPC
- decreased body weight / IMPC
- abnormal lens morphology / IMPC
- cataract / IMPC
- abnormal coat/hair pigmentation / IMPC
- abnormal eye morphology / IMPC
- abnormal tooth morphology / IMPC
- increased heart weight / IMPC
- decreased heart weight / IMPC
- increased circulating alanine transaminase level / IMPC
- abnormal humerus morphology / IMPC
- abnormal incisor color / IMPC
- decreased bone mineral content / IMPC
B6Dnk;B6Brd;B6N-Tyrc-Brd Sparctm1a(EUCOMM)Wtsi/WtsiCnbc
Status | Available to order |
EMMA ID | EM:05296 |
International strain name | B6Dnk;B6Brd;B6N-Tyrc-Brd Sparctm1a(EUCOMM)Wtsi/WtsiCnbc |
Alternative name | EPD0060_1_A07 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Sparctm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Sparc |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0060_1_A07. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Osteogenesis imperfecta type 4 / Orphanet_216820
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
- abnormal tibia morphology / MGI
- decreased body weight / MGI
- abnormal lens morphology / MGI
- cataract / MGI
- abnormal coat/hair pigmentation / MGI
- abnormal eye morphology / MGI
- abnormal tooth morphology / MGI
- abnormal humerus morphology / MGI
- decreased mean corpuscular hemoglobin concentration / MGI
- abnormal incisor color / MGI
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