- increased bone mineral density / IMPC
- decreased circulating LDL cholesterol level / IMPC
- decreased circulating HDL cholesterol level / IMPC
- decreased monocyte cell number / IMPC
- decreased body weight / IMPC
- abnormal lens morphology / IMPC
- cataract / IMPC
- increased circulating free fatty acid level / IMPC
- decreased circulating alanine transaminase level / IMPC
- increased circulating glycerol level / IMPC
- increased T cell number / IMPC
- decreased circulating cholesterol level / IMPC
- decreased circulating aspartate transaminase level / IMPC
- increased NK T cell number / IMPC
- increased CD8-positive, alpha-beta T cell number / IMPC
C57BL/6NTac-Trmt10atm1a(EUCOMM)Wtsi/WtsiOulu
Status | Available to order |
EMMA ID | EM:05441 |
International strain name | C57BL/6NTac-Trmt10atm1a(EUCOMM)Wtsi/WtsiOulu |
Alternative name | EPD0140_1_C09 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Trmt10atm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Trmt10a |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0140_1_C09. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | University of Oulu, Oulu, Finland |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Primary microcephaly-mild intellectual disability-young-onset diabetes syndrome / Orphanet_391408
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
- decreased circulating LDL cholesterol level / MGI
- decreased circulating HDL cholesterol level / MGI
- decreased body weight / MGI
- abnormal lens morphology / MGI
- cataract / MGI
- increased circulating free fatty acid level / MGI
- decreased circulating alanine transaminase level / MGI
- increased circulating glycerol level / MGI
- decreased circulating cholesterol level / MGI
- decreased circulating aspartate transaminase level / MGI
- increased sacral vertebrae number / MGI
- increased circulating magnesium level / MGI
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