129S5-Cochtm1Wtsi/WtsiCnrm

Status

Available to order

EMMA IDEM:06298
International strain name129S5-Cochtm1Wtsi/WtsiCnrm
Alternative nameCHOCHO
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolCochtm1Wtsi,
Gene/Transgene symbolCoch

Information from provider

ProviderKaren Steel
Provider affiliationWellcome Trust Sanger Institute
Additional ownerLorraine Everett and Ilona Zvetkova produced this line while employed by WTSI.
Genetic informationThis line carries a targeted mutation disrupting the Coch gene.
Phenotypic informationThis mutant may show hearing loss, but it has not been well-studied yet.
Breeding historyBelieved to have been maintained on a pure 129S5 genetic background.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Autosomal dominant non-syndromic sensorineural deafness type DFNA / Orphanet_90635

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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