B6.Cg-Tg(Rax-cre)1Zkoz/Ph
| Status | Available to order |
| EMMA ID | EM:06880 |
| International strain name | B6.Cg-Tg(Rax-cre)1Zkoz/Ph |
| Alternative name | C57BL/6-Tg(mRx-Cre)1Zkoz |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Rax-cre)1Zkoz, |
| Gene/Transgene symbol | Tg(Rax-cre)1Zkoz |
Information from provider
| Provider | Zbynek Kozmik |
| Provider affiliation | Dept. of Transcriptional Regulation, Institute of Molecular Genetics AS CR, v.v.i. |
| Genetic information | A BAC clone (RP24-82D21) containing 200kb covering the mouse Rx locus was modified by insertion of Cre recombinase into the first ATG of the Rx gene. The Cre-inserted BAC was used for pronuclear injection. |
| Phenotypic information | Cre recombinase is expressed in the pattern corresponding to the endogenous Rx gene: in optic vesicles and ventral forebrain from E9.0 embryos and later in retina and ventral forebrain. |
| Breeding history | This mouse strain was crossed 4x to C57BL/6NCrl. Breeding takes place only by crossing WT x tg mice. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6N Tac |
| Breeding at archiving centre | Transgenic males were put into breeding to generate "proven breeders". Males were used for sperm freezing and for IVF to generate embryos for freezing. |
| Stage of embryos | 2-cell |