B6.Cg-Tg(Tek-cre/ERT2)1Arnd/ArndCnrm
Status | Available to order |
EMMA ID | EM:00715 |
International strain name | B6.Cg-Tg(Tek-cre/ERT2)1Arnd/ArndCnrm |
Alternative name | Tie2CreERT2 |
Strain type | Transgenic Strains |
Allele/Transgene symbol | Tg(Tek-cre/ERT2)1Arnd, |
Gene/Transgene symbol | Tg(Tek-cre/ERT2)1Arnd |
Information from provider
Provider | Bernd Arnold |
Provider affiliation | German Cancer Research Center |
Genetic information | Expression of the Tie2CreERT2 transgene: 2.1 kb Tek (Tie2) promoter, 1.5 kb cre recombinase-ERT2 and 10.5 kb enhancer. |
Phenotypic information | No phenotype defects observed. Temporal cre-mediated recombination exclusively in endothelial cells using Tek (Tie2) regulatory elements. |
Breeding history | Mice have been backcrossed to C57BL/6 for over 6 generations. Currently, we either mate these mice with each other or with C57BL/6. |
References |
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Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Animals used for archiving | heterozygous C57BL/6, wild-type C57BL/6J |
Stage of embryos | 2-cell |
Literature references
- Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements.;Forde Anne, Constien Rainer, Gröne Hermann-Josef, Hämmerling Günter, Arnold Bernd, ;2002;Genesis (New York, N.Y. : 2000);33;191-7; 12203917
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