- decreased bone mineral density / IMPC
- increased circulating LDL cholesterol level / IMPC
- increased leukocyte cell number / IMPC
- increased monocyte cell number / IMPC
- decreased body length / IMPC
- increased circulating serum albumin level / IMPC
- increased circulating alkaline phosphatase level / IMPC
- thrombocytopenia / IMPC
- abnormal bone structure / IMPC
- decreased lean body mass / IMPC
- increased B cell number / IMPC
- increased circulating cholesterol level / IMPC
- improved glucose tolerance / IMPC
- increased circulating bilirubin level / IMPC
- decreased circulating glucose level / IMPC
- increased mean corpuscular hemoglobin / IMPC
- increased hemoglobin content / IMPC
- decreased NK T cell number / IMPC
- increased NK cell number / IMPC
- increased mature B cell number / IMPC
- decreased gamma-delta T cell number / IMPC
- increased circulating iron level / IMPC
- decreased red blood cell distribution width / IMPC
- decreased circulating fructosamine level / IMPC
- decreased bone mineral content / IMPC
- decreased effector memory CD8-positive, alpha-beta T cell number / IMPC
- increased KLRG1-positive NK cell number / IMPC
- increased Ly6C high monocyte number / IMPC
- increased Ly6C low monocyte number / IMPC
- decreased memory-marker CD4-negative NK T cell number / IMPC
- decreased CD4-positive NK T cell number / IMPC
- decreased memory-marker CD4-positive NK T cell number / IMPC
C57BL/6N-Atm1Brd Clpptm1a(EUCOMM)Wtsi/WtsiH
Status | Available to order |
EMMA ID | EM:09701 |
International strain name | C57BL/6N-Atm1Brd Clpptm1a(EUCOMM)Wtsi/WtsiH |
Alternative name | EPD0665_3_D05 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Clpptm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Clpp |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0665_3_D05. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Perrault syndrome / Orphanet_2855
IMPC phenotypes (allele matching)
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