C57BL/6J-Tg(tetO-ARAP1,-luc)1Rttr/H
| Status | Available to order |
| EMMA ID | EM:09785 |
| International strain name | C57BL/6J-Tg(tetO-ARAP1,-luc)1Rttr/H |
| Alternative name | Arap1-tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(tetO-ARAP1,-luc)1Rttr |
| Gene/Transgene symbol | Tg(tetO-ARAP1,-luc)1Rttr |
Information from provider
| Provider | Guy Rutter |
| Provider affiliation | Section of Cell Biology, Department of Medicine, Imperial College London |
| Genetic information | Insertion of a coding cassette under the control of a bidirectional tetracycline-regulated promoter driving the expression of both human flag-ARAP1 and firefly luciferase. Vector used for the subcloning of the transgene incorporated on this strain: pBI-L Vector PT3069-5 GenBank Accession No.:U89934 Catalog No. 631005. |
| Phenotypic information | Homozygous:N/AHeterozygous:Overexpression of the transgene after crossing with mice expressing the reverse tetracycline transactivator and given doxycycline in drinking water (possibility of inducing overexpression in a specific tissue). |
| Breeding history | Founder crossed with wild-type C57BL/6J to obtain F1; F1 crossed with wild-type C57BL/6J to obtain F2 to ensure the stability of the line (only one insertion site in the genome). |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |