C3H.C-Phf11dm1H/H
| Status | Available to order |
| EMMA ID | EM:09935 |
| International strain name | C3H.C-Phf11dm1H/H |
| Alternative name | Phf11d V103A |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Phf11dm1H, |
| Gene/Transgene symbol | Phf11d |
Information from provider
| Provider | Janet Kenyon |
| Provider affiliation | MRC Harwell |
| Genetic information | ENU point mutation affected Phf11d (valine 103 substitution for alanine). |
| Phenotypic information | Homozygous:None. On exposure to LPS mice have altered immune response in lungs compared to that seen in control mice (an asthma related phenotype.)Heterozygous:None |
| Breeding history | Mutation was induced on BALB/c, subsequently back crossed 10 generations onto C3H/HeH |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant.;Zhang Youming, Dean Charlotte, Chessum Lauren, Nguyen Dao, Stewart Michelle, Taylor Martin, Cookson William O, Moffatt Miriam F, ;2014;Mammalian genome : official journal of the International Mammalian Genome Society;25;573-82; 25091723