- hypoglycemia / MGI
- enlarged liver / MGI
- abnormal hepatocyte morphology / MGI
- muscle weakness / MGI
- hypoactivity / MGI
- premature death / MGI
- increased circulating alanine transaminase level / MGI
- increased circulating alkaline phosphatase level / MGI
- liver fibrosis / MGI
- increased circulating aspartate transaminase level / MGI
- decreased grip strength / MGI
- increased circulating creatine kinase level / MGI
- increased liver glycogen level / MGI
- increased skeletal muscle glycogen level / MGI
- increased cardiac muscle glycogen level / MGI
C57BL/6N-Agltm1a(EUCOMM)Wtsi/H
Status | Available to order |
EMMA ID | EM:05784 |
International strain name | C57BL/6N-Agltm1a(EUCOMM)Wtsi/H |
Alternative name | EPD0371_2_E12 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Agltm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Agl |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0371_2_E12. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTac |
Breeding at archiving centre | Chimeras were mated to C57BL/6N Tac USA and maintained on this background thereafter. |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- Glycogen storage disease due to glycogen debranching enzyme deficiency / Orphanet_366
MGI phenotypes (allele matching)
Information on how we integrate external resources can be found here
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