On this webpage you can find a submission form, which you should complete and send to EMMA via the website. On the submission form you will be asked to give information on depositor and owner, mutation(s), phenotype, genetic background and sanitary status of your mouse/rat strains, literature references, scientific interest and intellectual property rights, as well as some additional information that is needed for handling the animals.
Upon sending your submission you will receive an automatic email notification. Applications for archiving are evaluated by an external Evaluation Committee and, if the information provided through the submission form is clear enough, EMMA will contact you within 60 days and discuss how to proceed. Do not hesitate to contact
The European Mutant Mouse Archive (EMMA) welcomes submissions of mutant mouse and rat strains from all over the world, archives free of charge and facilitates global distribution.
You can submit your strains to EMMA here:
Deposit your mutant strain
Please use the online submission form to submit your strains to EMMA. The submission form captures information on depositor and owner, mutation(s), phenotype, genetic background, literature references, strain characterization, scientific interest, intellectual property rights and some additional information that is needed for handling the animals. Genotyping protocol and health certificate will be requested during the submission. Receipt of the online submission form will be confirmed by an automatic email notification.
Please note that CRISPR strains can be only considered for evaluation if peer-reviewed phenotypic information is available.
Mutant strains submitted for archiving are evaluated by INFRAFRONTIER’s external Evaluation Committee, which is composed of experts in the field of mouse genetics. They evaluate each submission to the EMMA repository, thereby ensuring that the research community has access to valuable mouse and rat mutant strains with significance for current and future genetic research. Major evaluation criteria are: sound scientific methods, evidence of heritability, identifiable genotype, and stabilised phenotype. If the information provided through the online submission form is clear enough, EMMA will inform depositors about the outcome of the evaluation within 60 days.
Requirements for Cryopreservation
Once approval has been granted, depositors have to provide a health status report for the mice or rats they want to send to EMMA. This report must be less than 3 months old. In the case of mouse lines, due to its methodological simplicity and reduced costs, for most strains sperm will be cryopreserved. Depositors are then asked to send a minimum of 5 heterozygous or homozygous males (as appropriate) of breeding age to the EMMA node to which the mutant line has been assigned to for cryopreservation. Embryo cryopreservation will only be considered in special cases where the strain background may not be available in the archiving centre in order to preserve the genetic background upon recovery and/or for strains containing several mutations. If a strain needs to be frozen down as embryos a minimum of 5 males and 5 females is required. Provision of more mice than the specified minimum will accelerate the freezing process. Under normal circumstances it will take EMMA between 4 and 6 months to freeze down a heterozygous mutant strain once the archiving centre has received the animals. This time frame includes a viability control.
Intellectual Property Rights
Deposited lines are archived under the EMMA repository conditions. EMMA only acts as distributor and any already existing Material Transfer Agreement will remain in full force and effect.
The EMMA cryopreservation service is free of charge. However, customers have to cover the actual costs for shipping material to the assigned EMMA node, which will usually be the one that is closer to the depositor. You can get the list of EMMA locations by selecting the service ‘EMMA node’ in the second filter.
Nomenclature Service and Integrated Resources
Depositors should be aware that to aid curation of archived strains, official nomenclature (including laboratory code) will be requested from Mouse Genome Informatics (MGI) when required. All registered alleles etc. will remain reserved, but not public on the MGI website, until they appear in any publication, or the strain is made public on the INFRAFRONTIER website.
In the following link you will find an overview about the nomenclature services offered by EMMA and the different resources integrated in order to enrich the information related to EMMA strains.
Nomenclature service and integrated resources