INFRAFRONTIER is the European Research Infrastructure for Modelling Human Diseases

We contribute to human health by advancing disease prevention and therapies through appropriate models.

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Cryopreservation Protocols EMMA Cre-driver EUCOMM IMPC Rare Disease COVID-19 Cancer

About INFRAFRONTIER

The INFRAFRONTIER consortium consists of more than 20 leading biomedical research institutes in 15 countries working together to understand basic mammalian gene function and model human diseases.

EMMA

The European Mouse Mutant Archive – EMMA is a non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant mouse and rat strains essential for basic biomedical research.

Resources and Services

In addition to EMMA, INFRAFRONTIER offers other services like axenic derivation, access to open calls and systemic phenotyping.

Animal Welfare and Ethics

Discover INFRAFRONTIER’s commitment to Animal Welfare and explore the ethical research practices we apply to drive the 3R Principle in animal research.

In the Spotlight

NEW

Open Call for Transnational Service Provision

Researchers are welcome to apply to a portfolio of services offered by canSERV to address the research needs of the entire oncology developmental pipeline. Deadline: 15 July.

INFRAPLUS

A Horizon-INFRA-DEV project that aims to expand INFRAFRONTIER’s capacity for human disease modelling, refine its service portfolio by reducing animal usage and developing alternative cellular models, and optimise the use of resources.

INFRAFRONTIER Cancer Services

Via the canSERV project, INFRAFRONTIER offers access to several cutting-edge cancer services as Open Calls. These services are offered by INFRAFRONTIER partners with world-leading expertise in cancer research and mouse models.

Axenic Service

This service offers the germ-free derivation of user-provided mouse strains for gnotobiotic studies.

Rodent Model Generation

Generation of custom rodent mutant strains using the latest genome-editing technologies by expert laboratories.

IMPC

INFRAFRONTIER is closely linked to the largest and foremost scientific consortium for mouse phenotyping worldwide – the International Mouse Phenotyping Consortium (IMPC).

Strain Distribution

Prices, Delivery Times, Legal Questions and everything you need to know before ordering mutant strains from us.

Strain Collections

Strains originated by large-scale projects archived and distributed by EMMA.

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INFRAFRONTIER Consortium

Upcoming Trainings & Events

EventOn-site

FELASA 2025

02 - 05 June 2025

FELASA

Athens, Greece

Asrar Ali Khan, Auke Boersma, Tania Sorg & Maik Dahlhoff

On-siteTraining

Mouse Necropsy

16 June 2025

Advance at MRC Harwell

MRC Harwell, Oxfordshire, UK

On-siteTraining

Mouse Genetics and Colony Management for Animal Technologists

01 - 02 July 2025

Advance at MRC Harwell

MRC Harwell, Oxfordshire

Latest News

Highlight May 13, 2025

EMMA Steps Up: Making Mutant Mouse Strains Easier to Track with RRIDs

Our EMMA repository now includes Research Resource Identifiers (RRIDs) for each mouse strain, enhancing traceability, reproducibility, and scientific rigor. This key update supports global research standards and reinforces INFRAFRONTIER’s mission in advancing trustworthy biomedical discovery.

Event May 9, 2025

PRIM-TECH3R Kick-off: Shaping the Future of the 3Rs in Preclinical Research

Just one month after its official start, PRIM-TECH3R kicked off with energy and one clear direction. Over the next four years, this EU-funded project will drive innovation in preclinical in vitro models, advancing the 3Rs and reshaping biomedical research across Europe.

Event May 6, 2025

INFRAFRONTIER Conference 2025: A Milestone in Our Commitment to Rare Disease Research

The INFRAFRONTIER Conference 2025 gathered over 100 participants and top experts in rare diseases for two inspiring days of science, discussion, and networking in Munich. Cutting-edge models, translational research, and European collaboration shaped a memorable event. See you in 2026!

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