INFRAFRONTIER is the European Research Infrastructure for Modelling Human Diseases

We contribute to human health by advancing disease prevention and therapies through appropriate models.

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The INFRAFRONTIER consortium consists of more than 20 leading biomedical research institutes in 15 countries working together to understand basic mammalian gene function and model human diseases.


The European Mouse Mutant Archive – EMMA is the INFRAFRONTIER’s non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant mouse strains essential for basic biomedical research.


In addition to EMMA, INFRAFRONTIER offers other services like axenic derivation, access to open calls and systemic phenotyping.

Resources and Services Spotlight



This ISIDORe Open Call provides extensive user support to the selected projects to assess novel potential vaccine and treatment compounds for COVID-19 in preclinical mouse models.


Axenic Service

This service offers the germ-free derivation of user-provided mouse strains for gnotobiotic studies.

COVID-19 Resources and Services

INFRAFRONTIER offers a cutting-edge COVID-19 therapeutics pipeline, a large selection of COVID-19-related strains and emergency archiving services to aid COVID-19 research and minimise the loss of valuable mouse strains.

INFRAFRONTIER and Cancer Research

Browse through EMMA strains associated to more than 50 different cancer types and a list of manually-curated disease models for cancer.

INFRAFRONTIER and Rare Diseases

Access to over 1700 mouse strains (via EMMA) that are related to more than 1300 distinct rare diseases. Find the right model for the right disease.


INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).