MGI phenotypes (allele matching)
STOCK Nototm2.1(Foxj1)Gos/Kctt
| Status | Available to order |
| EMMA ID | EM:10414 |
| Citation information | RRID:IMSR_EM:10414 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Nototm2.1(Foxj1)Gos/Kctt |
| Alternative name | Noto tm2.1(Foxj1)Gos |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Nototm2.1(Foxj1)Gos |
| Gene/Transgene symbol | Noto |
Information from provider
| Provider | Achim Gossler |
| Provider affiliation | Medizinische Hochschule Hannover |
| Genetic information | Foxj1 knock-in into the Noto locus |
| Phenotypic information | Homozygous:to be updatedHeterozygous:to be updated |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | heterozygous males |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal vertebrae morphology / MGI
- kinked tail / MGI
- short tail / MGI
- hindlimb paralysis / MGI
- abnormal floor plate morphology / MGI
- abnormal dorsal root ganglion morphology / MGI
- decreased caudal vertebrae number / MGI
- abnormal blood vessel morphology / MGI
- abnormal somite development / MGI
- abnormal left-right axis patterning / MGI
- postnatal lethality / MGI
- premature death / MGI
- abnormal tail morphology / MGI
- curly tail / MGI
- absent tail / MGI
- abnormal primitive node morphology / MGI
- abnormal motile primary cilium morphology / MGI
- fusion of vertebral bodies / MGI
- decreased vertebrae number / MGI
- decreased lumbar vertebrae number / MGI
- truncated notochord / MGI
- embryo phenotype / MGI
- skeleton phenotype / MGI
- abnormal sclerotome morphology / MGI
- abnormal motile primary cilium physiology / MGI
- decreased embryonic cilium length / MGI
- abnormal embryonic cilium location or orientation / MGI
- absent nodal flow / MGI
Literature references
- Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.;Alten Leonie, Schuster-Gossler Karin, Beckers Anja, Groos Stephanie, Ulmer Bärbel, Hegermann Jan, Ochs Matthias, Gossler Achim, ;2012;Development (Cambridge, England);139;1276-84; 22357932