B6;129-Wnt4tm4Svo/Oulu

Status

Available to order

EMMA IDEM:10574
Citation informationRRID:IMSR_EM:10574 

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International strain nameB6;129-Wnt4tm4Svo/Oulu
Alternative nameWnt4 3'UTR
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolWnt4tm4Svo
Gene/Transgene symbolWnt4

Information from provider

ProviderJingdong Shan
Provider affiliationDepartment of Biochemistry and Molecular Medicine, University of Oulu
Genetic informationWnt4 3'UTR construct, containing three PolyA sequences in a row, was targeted to the stop codon of Wnt4 locus in 129/Sv ES cells.
Phenotypic informationHomozygous:
Wnt4 3'UTR homozygotes show a slight phenotype in the urogenital system.

Heterozygous:
Heterozygous mice have no reported phenotypes.
ReferencesNone available
Homozygous fertilenot known
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreUniversity of Oulu, Oulu, Finland
Animals used for archivingheterozygous males, wild-type females
Stage of embryos2-cell

Disease and phenotype information

MGI phenotypes (gene matching)
  • absent kidney / MGI
  • abnormal kidney development / MGI
  • delayed kidney development / MGI
  • decreased thymocyte number / MGI
  • abnormal ovary morphology / MGI
  • abnormal oogenesis / MGI
  • secondary sex reversal / MGI
  • no abnormal phenotype detected / MGI
  • abnormal secondary sex determination / MGI
  • abnormal adrenal gland physiology / MGI
  • no phenotypic analysis / MGI
  • kidney failure / MGI
  • nervous system phenotype / MGI
  • abnormal reproductive system development / MGI
  • abnormal adenohypophysis morphology / MGI
  • decreased renal glomerulus number / MGI
  • decreased oocyte number / MGI
  • abnormal female germ cell morphology / MGI
  • absent Mullerian ducts / MGI
  • decreased somatotroph cell number / MGI
  • decreased gonadotroph cell number / MGI
  • decreased thyrotroph cell number / MGI
  • oocyte degeneration / MGI
  • abnormal metanephric mesenchyme morphology / MGI
  • abnormal nephrogenic mesenchyme morphogenesis / MGI
  • postnatal lethality, complete penetrance / MGI
  • neonatal lethality, complete penetrance / MGI
  • small metanephros / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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