MGI phenotypes (gene matching)
- increased susceptibility to viral infection / MGI
C57BL/6N-Xpr1tm1a(KOMP)Wtsi/Ph
| Status | Available to order |
| EMMA ID | EM:10578 |
| Citation information | RRID:IMSR_EM:10578 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Xpr1tm1a(KOMP)Wtsi/Ph |
| Alternative name | C57Bl/6NCrl-Xpr1tm1a(KOMP)Wtsi |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Xpr1tm1a(KOMP)Wtsi |
| Gene/Transgene symbol | Xpr1 |
Information from provider
| Provider | Natividad Hernando |
| Provider affiliation | Institute of Physiology, University of Zurich |
| Genetic information | Conditional knockout of Xpr1 gene. Knockout first allele (reporter-tagged insertion with conditional potential). Exon 2 of Xpr1 gene is flanked by loxP site. LacZ reporter cassette and neomycin selection cassette in front of exon 2 are flanked by Frt sites. |
| Phenotypic information | Homozygous:not knownHeterozygous:Heterozygous mice appear normal and do not show any gross phenotype. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6NCrl males, wild-type females |
| Breeding at archiving centre | Allele kept on heterozygous basis, crossed with C57BL/6N partners. Heterozygous males used for IVF to perform embryo freezing. |
| Stage of embryos | 2-cell |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Bilateral striopallidodentate calcinosis / Orphanet_1980