| Status | Available to order |
| EMMA ID | EM:10726 |
| Citation information | RRID:IMSR_EM:10726 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C.129P2-Alas1Gt(YTA357)Byg/ToxH |
| Alternative name | BALB/c Alas1-bGEO |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Alas1Gt(YTA357)Byg |
| Gene/Transgene symbol | Alas1 |
| Provider | Andrew Smith |
| Provider affiliation | MRC Toxicology Unit/University of Leicester, MRC |
| Genetic information | Gene trap of ALAS1 allele generated from ES cells (cell line ID: YTA357) by Bay Genomics resource. The pGT0lxf vector was inserted within the intron between exon3 and exon4 of ALAS1. The insert contains the En2 splice acceptor, the beta-galactosidase-neomycin fusion protein gene (bGEO), the ampicillin resentence gene (AmpR) and the SV40 polyadenylation site. Heterozygous cell line was recovered during electroporation then chimeras were produced at Geneta, University of Leicester. |
| Phenotypic information | Homozygous:Lethal by embryo day 12Heterozygous:Apparently normal |
| Breeding history | Backcrossed on to BALB/c |
| References | None available |
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
