FVB/N-Tg(CAG-Itga11)1Dgul/Kctt
| Status | Available to order |
| EMMA ID | EM:10886 |
| Citation information | RRID:IMSR_EM:10886 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB/N-Tg(CAG-Itga11)1Dgul/Kctt |
| Alternative name | FVB/N-Tg(CAG-Itga11)Dgul |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CAG-Itga11)1Dgul |
| Gene/Transgene symbol | Tg(CAG-Itga11)1Dgul |
Information from provider
| Provider | Donald Gullberg |
| Provider affiliation | Biomedicine, University of Bergen |
| Genetic information | A 7kb DNA fragment with full-length mouse integrin alpha 11 cDNA with 3’-UTR (4.9 kb) downstream of the CAG promoter was excised from the pCAGGS-Itga11 construct using SalI and NotI endonucleases for injection. Transgenic mice were generated by pronuclear injection at the Transgene Core Facility, Biocenter Oulu, Finland. The established transgenic strain was then transported to University of Bergen, Norway and maintained there for experiments. |
| Phenotypic information | Homozygous:Not relevant. The transgenic mice have always been bred with their wild-type littermates.Heterozygous:Not relevant. The mice are transgenic. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Literature references
- Overexpression of integrin α11 induces cardiac fibrosis in mice.;Romaine A, Sørensen I W, Zeltz C, Lu N, Erusappan P M, Melleby A O, Zhang L, Bendiksen B, Robinson E L, Aronsen J M, Herum K M, Danielsen H E, Sjaastad I, Christensen G, Gullberg D, ;2018;Acta physiologica (Oxford, England);222;; 28771943