B6.Cg-Tg(KRT14-Lgals7)34Ijmfp/Cnbc

Status	Available to order
EMMA ID	EM:10966
Citation information	RRID:IMSR_EM:10966 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6.Cg-Tg(KRT14-Lgals7)34Ijmfp/Cnbc
Alternative name	Tg-K14galectin7
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(KRT14-Lgals7)34Ijmfp
Gene/Transgene symbol	Tg(KRT14-Lgals7)34Ijmfp

Information from provider

Provider	francoise POIRIER
Provider affiliation	UMR 7592 CNRS-Université Paris Diderot, Institut Jacques Monod
Genetic information	As described in Gendronneau 2015, C57BL/6;DBA/2 oocytes were microinjected with a construct containing the rat galectin-7 cDNA placed downstream of the keratin14 (K14) promoter (Saitou et al., 1995).
Phenotypic information	Homozygous: Normal lifespan, mild epidermis defects. Heterozygous: Normal lifespan, mild epidermis defects.
Breeding history	Founder animals carrying the transgene were mated with C57BL/6 individuals and two independent K14-galectin-7 transgenic lines. Tg34 was established after eight successive backcrosses on the C57BL/6 background.
References	Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair.;Gendronneau Gaëlle, Sanii Sadaf, Dang Tien, Deshayes Frédérique, Delacour Delphine, Pichard Evelyne, Advedissian Tamara, Sidhu Sukhvinder S, Viguier Mireille, Magnaldo Thierry, Poirier Francoise, ;2015;PloS one;10;e0119031; 25741714
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archiving	homozygous C57BL/6J males

Literature references

Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair.;Gendronneau Gaëlle, Sanii Sadaf, Dang Tien, Deshayes Frédérique, Delacour Delphine, Pichard Evelyne, Advedissian Tamara, Sidhu Sukhvinder S, Viguier Mireille, Magnaldo Thierry, Poirier Francoise, ;2015;PloS one;10;e0119031; 25741714

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Genotyping protocol

Example health report
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Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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