PASK-flox
| Status | Available to order |
| EMMA ID | EM:11191 |
| Citation information | RRID:IMSR_EM:11191 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | PASK-flox |
| Alternative name | PASK-flox |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Pasktm-Gsxil |
| Gene/Transgene symbol | Pask |
Information from provider
| Provider | Gabriela da Silva Xavier |
| Provider affiliation | Cell Biology, Imperial College London |
| Genetic information | Mice carrying conditional null alleles of Pask (Paskfl/fl) were generated by insertion of loxP sites flanking exon 11 and exon 15, which encompass the Ser/Thr kinase domain, through homologous recombination |
| Phenotypic information | Homozygous:No obvious phenotypeHeterozygous:No obvious phenotype |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production.;Semplici Francesca, Mondragon Angeles, Macintyre Benedict, Madeyski-Bengston Katja, Persson-Kry Anette, Barr Sara, Ramne Anna, Marley Anna, McGinty James, French Paul, Soedling Helen, Yokosuka Ryohsuke, Gaitan Julien, Lang Jochen, Migrenne-Li Stephanie, Philippe Erwann, Herrera Pedro L, Magnan Christophe, da Silva Xavier Gabriela, Rutter Guy A, ;2016;Diabetologia;59;1938-47; 27338626