B6N;129-Kaptm1Msgr/Cnbc
| Status | Available to order |
| EMMA ID | EM:11250 |
| Citation information | RRID:IMSR_EM:11250 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6N;129-Kaptm1Msgr/Cnbc |
| Alternative name | KO-KAP |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Kaptm1Msgr |
| Gene/Transgene symbol | Kap |
Information from provider
| Provider | Anna Meseguer Navarro |
| Provider affiliation | Vall d’Hebron Barcelona Hospital |
| Additional owner | Manoocher Soleimani, University of Cincinnati Department: Internal Medicine-Nephrology & Hypertension, US |
| Genetic information | Targeted iTL BA1 (C57BL/6N x 129/SvEv) hybrid embryonic stem cells were microinjected into C57BL/6 blastocysts. Resulting chimeras with a high percentage agouti coat color were mated to wild-type C57BL/6N mice to generate F1 heterozygous offspring. See details of targeting vector and targeted mutant allele in the genotyping protocol file. |
| Phenotypic information | Homozygous:The phenotype is under study. We expect to have hypotensive mice since the transgenic KAP mice are hypertensive.Heterozygous:The phenotype is under study. We expect to have hypotensive mice since the transgenic KAP mice are hypertensive. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6N males |