BALB/c-Rb(8.12)5Bnr/H

Status	Available to order
EMMA ID	EM:11359
Citation information	RRID:IMSR_EM:11359 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	BALB/c-Rb(8.12)5Bnr/H
Alternative name	Rb(8.12)5Bnr_BALB/c
Strain type	Chromosomal Anomalies
Allele/Transgene symbol	Rb(8.12)5Bnr
Gene/Transgene symbol	Rb(8.12)5Bnr

Information from provider

Provider	Anne Ferguson-Smith
Provider affiliation	Genetics, University of Cambridge
Genetic information	Robertsonian translocation between chromosomes 8 and 12.
Phenotypic information	Homozygous: None Heterozygous: None
Breeding history	In the 1970s, feral animals with spontaneous Robertsonian translocations were bred to homozygosity and provided by the late Professor H. Winking (Institut für Biologie, Universität Lübeck, Lübeck). They have been maintained by Anne Ferguson-Smith since 1992.
References	Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12.;Georgiades P, Watkins M, Surani M A, Ferguson-Smith A C, ;2000;Development (Cambridge, England);127;4719-28; 11023874 Restricted co-expression of Dlk1 and the reciprocally imprinted non-coding RNA, Gtl2: implications for cis-acting control.;da Rocha Simão T, Tevendale Maxine, Knowles Edward, Takada Shuji, Watkins Marie, Ferguson-Smith Anne C, ;2007;Developmental biology;306;810-23; 17449025 Defective imprint resetting in carriers of Robertsonian translocation Rb (8.12).;Saferali Aabida, Berlivet Soizik, Schimenti John, Bartolomei Marisa S, Taketo Teruko, Naumova Anna K, ;2010;Mammalian genome : official journal of the International Mammalian Genome Society;21;377-87; 20577743 Dynamics of response to asynapsis and meiotic silencing in spermatocytes from Robertsonian translocation carriers.;Naumova Anna K, Fayer Shawn, Leung Jacky, Boateng Kingsley A, Camerini-Otero R Daniel, Taketo Teruko, ;2013;PloS one;8;e75970; 24066189 Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice.;Gropp A, Winking H, Zech L, Müller H, ;1972;Chromosoma;39;265-88; 4634355
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Literature references

Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12.;Georgiades P, Watkins M, Surani M A, Ferguson-Smith A C, ;2000;Development (Cambridge, England);127;4719-28; 11023874
Restricted co-expression of Dlk1 and the reciprocally imprinted non-coding RNA, Gtl2: implications for cis-acting control.;da Rocha Simão T, Tevendale Maxine, Knowles Edward, Takada Shuji, Watkins Marie, Ferguson-Smith Anne C, ;2007;Developmental biology;306;810-23; 17449025
Defective imprint resetting in carriers of Robertsonian translocation Rb (8.12).;Saferali Aabida, Berlivet Soizik, Schimenti John, Bartolomei Marisa S, Taketo Teruko, Naumova Anna K, ;2010;Mammalian genome : official journal of the International Mammalian Genome Society;21;377-87; 20577743
Dynamics of response to asynapsis and meiotic silencing in spermatocytes from Robertsonian translocation carriers.;Naumova Anna K, Fayer Shawn, Leung Jacky, Boateng Kingsley A, Camerini-Otero R Daniel, Taketo Teruko, ;2013;PloS one;8;e75970; 24066189
Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice.;Gropp A, Winking H, Zech L, Müller H, ;1972;Chromosoma;39;265-88; 4634355

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.
Not found what you were looking for? Search here for other strains available from EMMA.