CD2-Egr2 transgenic (Tg) mouse
| Status | Available to order |
| EMMA ID | EM:11390 |
| Citation information | RRID:IMSR_EM:11390 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | CD2-Egr2 transgenic (Tg) mouse |
| Alternative name | CD2-Egr2 transgenic (Tg) mouse |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(CD2-Egr2) |
| Gene/Transgene symbol | Tg(CD2-Egr2) |
Information from provider
| Provider | Suling Li |
| Provider affiliation | Life Science, Brunel University |
| Genetic information | Egr2 overexpressed under CD2 promoter; mice were generated on the C57BL/6 background (ref.: Miao t. et al., JEM, 2017; PMID:28487311). |
| Phenotypic information | Homozygous:The Egr2-Tg mice overexpress Egr2 under the CD2 promoter, so all T cells express the Egr2 gene. The mice show healthy breeding in general, although the thymus and spleen are smaller compared to wild-type mice. Some defects shown in adaptive immunity (ref.: Miao t. et al., JEM, 2017; PMID:28487311).Heterozygous:The mice show healthy breeding in general, although the thymus and spleen are smaller compared to wild-type mice. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |