B6.Cg-Fkrptm2Scbr/RvcH
| Status | Available to order |
| EMMA ID | EM:11610 |
| Citation information | RRID:IMSR_EM:11610 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Fkrptm2Scbr/RvcH |
| Alternative name | B6.Fkrptm1(IRES; EGFP)Rvc |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Fkrptm2Scbr |
| Gene/Transgene symbol | Fkrp |
Information from provider
| Provider | Susan Brown |
| Provider affiliation | Comparative Biomedical Sciences, Royal Veterinary College |
| Genetic information | Line has an IRES/GFP cassette inserted into exon 3 of Fkrp, immediately following the coding region. |
| Phenotypic information | Homozygous:As wild-type except for the expression of EGFP under the Fkrp promoterHeterozygous:As wild-type mice. |
| Breeding history | No breeding with other lines, maintained as a homozygous colony |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | homozygous C57BL/6 males |
| Breeding at archiving centre | The stock has been maintained on a C57BL/6 background |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Walker-Warburg syndrome / Orphanet_899
- Congenital muscular dystrophy with intellectual disability / Orphanet_370968
- Congenital muscular dystrophy with cerebellar involvement / Orphanet_370959
- FKRP-related limb-girdle muscular dystrophy R9 / Orphanet_34515
- Muscle-eye-brain disease / Orphanet_588
- Congenital muscular dystrophy without intellectual disability / Orphanet_370980
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