MGI phenotypes (allele matching)
C3H;C-Ta33Hl/H
| Status | Available to order |
| EMMA ID | EM:01170 |
| Citation information | RRID:IMSR_EM:01170 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3H;C-Ta33Hl/H |
| Alternative name | INH/6 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Ta33Hl |
| Gene/Transgene symbol | Ta33Hl |
Information from provider
| Provider | Neil Dear |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Genetic information | The Tabby mutation (anhidrotic ectodermal dysplasia) is a mouse model for X-linked hypohirotic ectodermal dysplasia. This is a congenital disorder resulting in abnormal tooth, hair and sweat gland development. Note: this may not be the case in this particular Tabby mutation as the teeth superficially appear to be normal. |
| Phenotypic information | Heterozygous females are striped. Hemizygous males have no guard hairs, hair on tails, normal teeth, very little hair behind the ears. Homozygous females look like hemizygous males. |
| Breeding history | Original background: C3H/HeH x BALB/c. Maintained background: C3H/HeH backcross. Breeding History: Backcrossed to C3H/HeH for several generations. |
| References |
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Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191