rat SD-Del(1Sult1a1-Spn)1Yah/YahIcsOrl
| Status | Available to order |
| EMMA ID | EM:11821 |
| Citation information | EM:11821 |
| International strain name | rat SD-Del(1Sult1a1-Spn)1Yah/YahIcsOrl |
| Alternative name | Sprague Dawley rat Rno1_Del(Sult1a1-Spn) |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | rat Del(1Sult1a1-Spn)1Yah |
| Gene/Transgene symbol | rat Del(1Sult1a1-Spn)1Yah |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | Translational Medicine and Neurogenetics, I.G.B.M.C. |
| Genetic information | Sprague-Dawley rat strain. Deletion of the genetic interval Sult1a1-Spn. We targeted an extended sequence of the whole locus from one allele and the CRISPR/Cas9 system allowed us to remove the region encompassing 28 genes, orthologous to human. |
| Phenotypic information | Homozygous:Homozygous rats were not generated.Heterozygous:Growth delay and hyperactive behaviour. |
| Breeding history | 1 backcross on Sprague-Dawley genetic background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous rat Sprague-Dawley males, wild-type rat Sprague-Dawley females |
| Stage of embryos | 2-cell |