B6;129S2-Epha4tm1Pch/Orl
| Status | Available to order |
| EMMA ID | EM:11830 |
| Citation information | RRID:IMSR_EM:11830 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S2-Epha4tm1Pch/Orl |
| Alternative name | EphA4 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Epha4tm1Pch |
| Gene/Transgene symbol | Epha4 |
Information from provider
| Provider | Carole Desmarquet-Trin-Dinh |
| Provider affiliation | Equipe Developpement du Systeme Nerveux IBENS, INSERM U 1024, CNRS UMR 8197, Ecole Normale Superieure |
| Genetic information | Insertion of lacZ in EphA4/Sek2 locus. |
| Phenotypic information | Homozygous:Abnormal hind limbs position (not fertile).Heterozygous:Sometimes heterozygotes have an abnormal hind limbs position (fertile). |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6 males, wild-type C57BL/6 females |
| Stage of embryos | 2-cell |
Literature references
- Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons.;Helmbacher F, Schneider-Maunoury S, Topilko P, Tiret L, Charnay P, ;2000;Development (Cambridge, England);127;3313-24; 10887087