STOCK Ebf3tm-KO/Orl

Status

Available to order

EMMA IDEM:11831
Citation informationRRID:IMSR_EM:11831 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameSTOCK Ebf3tm-KO/Orl
Alternative nameEbf3
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolEbf3-KO
Gene/Transgene symbolEbf3

Information from provider

ProviderCarole Desmarquet-Trin-Dinh
Provider affiliationEquipe Developpement du Systeme Nerveux IBENS, INSERM U 1024, CNRS UMR 8197, Ecole Normale Superieure
Genetic informationKnock-out of Ebf3 gene with insertion of neo gene
Phenotypic informationHomozygous:
Not viable

Heterozygous:
Nothing to report
Breeding historyMaintained on (C57BL/6 x DBA/2)F1 background.
References
  • Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.;Garel S, Marín F, Mattéi M G, Vesque C, Vincent A, Charnay P, ;1997;Developmental dynamics : an official publication of the American Association of Anatomists;210;191-205; 9389446
Homozygous fertileno
Homozygous viableno
Homozygous matings requiredyes
Immunocompromisedno

Information from EMMA

Archiving centreCNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France
Animals used for archivingheterozygous (C57BL/6 x DBA/2)F1 males, wild-type (C57BL/6 x DBA/2)F1 females
Stage of embryos2-cell

Disease and phenotype information

MGI phenotypes (gene matching)
  • abnormal sensory neuron innervation pattern / MGI
  • small olfactory bulb / MGI
  • neonatal lethality, complete penetrance / MGI

Literature references

  • Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.;Garel S, Marín F, Mattéi M G, Vesque C, Vincent A, Charnay P, ;1997;Developmental dynamics : an official publication of the American Association of Anatomists;210;191-205; 9389446

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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