B6.129S2-Del(2Hoxd11-Hoxd13)29Ddu/Orl

Status

Available to order

EMMA IDEM:01222
Citation informationRRID:IMSR_EM:01222 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameB6.129S2-Del(2Hoxd11-Hoxd13)29Ddu/Orl
Alternative nameB6.129 HoxD
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolDel(2Hoxd11-Hoxd13)29Ddu
Gene/Transgene symbolDel(2Hoxd11-Hoxd13)29Ddu

Information from provider

ProviderDuboule Denis
Provider affiliationLaboratoire Moléculaire et Morphogenèse
Genetic informationDeletion of Hoxd13 and Hoxd12 genomic region and insertion of an Hoxd11-lacZ transgene.
Phenotypic informationLimb defect.
References
  • Synpolydactyly in mice with a targeted deficiency in the HoxD complex.;Zákány J, Duboule D, ;1996;Nature;384;69-71; 8900279
  • Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.;Zákány J, Gérard M, Favier B, Duboule D, ;1997;The EMBO journal;16;4393-402; 9250683

Information from EMMA

Archiving centreCNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France

Disease and phenotype information

MGI phenotypes (allele matching)
  • polydactyly / MGI
  • brachydactyly / MGI
  • ectrodactyly / MGI
  • abnormal autopod morphology / MGI
  • abnormal digit morphology / MGI
  • delayed endochondral bone ossification / MGI
  • polysyndactyly / MGI
  • abnormal digit development / MGI
  • abnormal interdigital cell death / MGI
MGI phenotypes (gene matching)
  • polydactyly / MGI
  • abnormal autopod morphology / MGI
  • abnormal digit morphology / MGI
  • brachydactyly / MGI
  • delayed endochondral bone ossification / MGI
  • polysyndactyly / MGI
  • ectrodactyly / MGI
  • abnormal digit development / MGI
  • abnormal interdigital cell death / MGI

Literature references

  • Synpolydactyly in mice with a targeted deficiency in the HoxD complex.;Zákány J, Duboule D, ;1996;Nature;384;69-71; 8900279
  • Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.;Zákány J, Gérard M, Favier B, Duboule D, ;1997;The EMBO journal;16;4393-402; 9250683

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).