MGI phenotypes (allele matching)
B6.129S2-Evx2tm1Ddu/Orl
| Status | Available to order |
| EMMA ID | EM:01224 |
| Citation information | RRID:IMSR_EM:01224 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Evx2tm1Ddu/Orl |
| Alternative name | Evx2Ge |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Evx2tm1Ddu |
| Gene/Transgene symbol | Evx2 |
Information from provider
| Provider | Duboule Denis |
| Provider affiliation | Laboratoire Moléculaire et Morphogenèse |
| Genetic information | Mutation caused by the insertion of PGKhygro gene in exon 1 of the Evx2 gene. |
| Phenotypic information | Limb defect. |
| References |
|
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- short limbs / MGI
- abnormal forelimb morphology / MGI
- abnormal carpal bone morphology / MGI
- decreased body weight / MGI
- male infertility / MGI
- abnormal digit morphology / MGI
- brachyphalangia / MGI
- brachydactyly / MGI
- abnormal metacarpal bone morphology / MGI
- short radius / MGI
- short ulna / MGI
- bowed ulna / MGI
- bowed radius / MGI
- short metacarpal bones / MGI
- abnormal phalanx morphology / MGI
Literature references
- Function of the Evx-2 gene in the morphogenesis of vertebrate limbs.;Hérault Y, Hraba-Renevey S, van der Hoeven F, Duboule D, ;1996;The EMBO journal;15;6727-38; 8978698