MGI phenotypes (allele matching)
B6.129S2-Hoxd12tm2Ddu/Orl
| Status | Available to order |
| EMMA ID | EM:01225 |
| Citation information | RRID:IMSR_EM:01225 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Hoxd12tm2Ddu/Orl |
| Alternative name | Hoxd12lacZ |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Hoxd12tm2Ddu |
| Gene/Transgene symbol | Hoxd12 |
Information from provider
| Provider | Duboule Denis |
| Provider affiliation | Laboratoire Moléculaire et Morphogenèse |
| Genetic information | Fusion of the lacZ reporter gene in exon 1 of the Hoxd12 gene. |
| Phenotypic information | Limb defect. |
| Breeding history | Backcross: N=10; Intercross: N=10. |
| References |
|
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- short limbs / MGI
- abnormal forelimb morphology / MGI
- abnormal radius morphology / MGI
- abnormal carpal bone morphology / MGI
- abnormal hindlimb morphology / MGI
- abnormal tibia morphology / MGI
- oligodactyly / MGI
- abnormal smooth muscle morphology / MGI
- abnormal digit morphology / MGI
- abnormal fibula morphology / MGI
- brachyphalangia / MGI
- brachydactyly / MGI
- abnormal joint morphology / MGI
- short metacarpal bones / MGI
- short metatarsal bones / MGI
- abnormal ulna morphology / MGI
- abnormal phalanx morphology / MGI
- clinodactyly / MGI
- abnormal internal anal sphincter morphology / MGI
Literature references
- Function of posterior HoxD genes in the morphogenesis of the anal sphincter.;Kondo T, Dollé P, Zákány J, Duboule D, ;1996;Development (Cambridge, England);122;2651-9; 8787740