MGI phenotypes (allele matching)
- no phenotypic analysis / MGI
B6.129S2-Igs16tm1.1Ddu/Orl
| Status | Available to order |
| EMMA ID | EM:01226 |
| Citation information | RRID:IMSR_EM:01226 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Igs16tm1.1Ddu/Orl |
| Alternative name | VIII |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Igs16tm1.1Ddu |
| Gene/Transgene symbol | Igs16 |
Information from provider
| Provider | Duboule Denis |
| Provider affiliation | Laboratoire Moléculaire et Morphogenèse |
| Genetic information | The targeted deletion of region XII (intergenic site 16, Igs16), upstream of the Hoxd13 gene was engineered by homologous recombination in ES cells. |
| Phenotypic information | Limb defect. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
Literature references
- Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells.;Kmita Marie, Tarchini Basile, Duboule Denis, Hérault Yann, ;2002;Development (Cambridge, England);129;5521-8; 12403721