STOCK Mirc35tm1.1Pern/Kctt
| Status | Available to order |
| EMMA ID | EM:12387 |
| Citation information | RRID:IMSR_EM:12387 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Mirc35tm1.1Pern/Kctt |
| Alternative name | C57BL/6-Mir96_Mir182_Mir183(tm2014)Arte; Mirc35-tm1Arte |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Mirc35tm1.1Pern |
| Gene/Transgene symbol | Mirc35 |
Information from provider
| Provider | Patrik Ernfors |
| Provider affiliation | MBB, Karolinska Institutet |
| Genetic information | Floxed microRNA cluster 35 (Mir-183_Mir-96_Mir-182). |
| Phenotypic information | Homozygous:No phehotypeHeterozygous:No phehotype |
| Breeding history | The original background of the Mirc35 (miR-183-182-196) floxed mouse line is C57BL/6, then it got mixed genetic background when it was crossed with a Wnt1-cre line (Danielian PS et al., PMID:9843687), which is on B6CBA/J and 129/SvEv background. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | homozygous males |
Literature references
- miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.;Peng Changgeng, Li Lili, Zhang Ming-Dong, Bengtsson Gonzales Carolina, Parisien Marc, Belfer Inna, Usoskin Dmitry, Abdo Hind, Furlan Alessandro, Häring Martin, Lallemend Francois, Harkany Tibor, Diatchenko Luda, Hökfelt Tomas, Hjerling-Leffler Jens, Ernfors Patrik, ;2017;Science (New York, N.Y.);356;1168-1171; 28572455
- The miR-183/96/182 cluster regulates sensory innervation, resident myeloid cells and functions of the cornea through cell type-specific target genes.;Gupta Naman, Somayajulu Mallika, Gurdziel Katherine, LoGrasso Giovanni, Aziz Haidy, Rosati Rita, McClellan Sharon, Pitchaikannu Ahalya, Santra Manoranjan, Shukkur Muhammed Farooq Abdul, Stemmer Paul, Hazlett Linda D, Xu Shunbin, ;2024;Scientific reports;14;7676; 38561433
- New Insight Into the Neuroimmune Interplay In Pseudomonas aeruginosa Keratitis.;Gupta Naman, LoGrasso Giovanni, Hazlett Linda D, Xu Shunbin, ;2025;bioRxiv : the preprint server for biology;0;; 40161776