B6;129-Pcbp4tm1Geno/Cnbc
| Status | Available to order |
| EMMA ID | EM:12618 |
| Citation information | RRID:IMSR_EM:12618 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Pcbp4tm1Geno/Cnbc |
| Alternative name | Floxed-PCBP4 |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Pcbp4tm1Geno |
| Gene/Transgene symbol | Pcbp4 |
Information from provider
| Provider | Ruben Pio |
| Provider affiliation | Program in Solid Tumors, CIMA-University of Navarra |
| Additional owner | genOway, France |
| Genetic information | This is a mouse conditional mutant line targeting the Pcbp4 gene. The gene is located on chromosome 9 and extends on ca. 10 Kb. The gene is composed of 13 exons. The cDNA contains 1984 nucleotides. The open reading frame encodes for a 403 amino acid polypeptide. The translation initiation site is located in exon 2 and the stop codon in exon 13. A conditional gene targeting strategy (“Safe knock-out” approach from GenOway) was used to flank exons 2 to 12 (containing the three KH functional domains of the PCBP4 protein) by two loxP sites. Targeted GenOway 129/SvPas ES clones were generated and injected into C57BL/6 blastocysts. |
| Phenotypic information | Homozygous:Viable. No observed phenotypic variations.Heterozygous:Viable. No observed phenotypic variations. |
| Breeding history | The line has been maintained by intercrossing C57BL/6 homozygous mice. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | homozygous C57BL/6J males |