IMPC phenotypes (gene matching)
STOCK Cfap206tm1.1Gos/Biat
| Status | Available to order |
| EMMA ID | EM:12822 |
| Citation information | RRID:IMSR_EM:12822 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Cfap206tm1.1Gos/Biat |
| Alternative name | Cfap206 plox |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Cfap206tm1.1Gos |
| Gene/Transgene symbol | Cfap206 |
Information from provider
| Provider | Achim Gossler |
| Provider affiliation | MHH |
| Genetic information | Conditional allele; exon 4 flanked by loxP sites |
| Phenotypic information | Homozygous:No phenotype detected; ciliary defects after deletion of exon 4.Heterozygous:No phenotype detected |
| Breeding history | More than 10 generations including CD1 and B6 |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous Other (please specify below) males |
Disease and phenotype information
Literature references
- The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development.;Beckers Anja, Adis Christian, Schuster-Gossler Karin, Tveriakhina Lena, Ott Tim, Fuhl Franziska, Hegermann Jan, Boldt Karsten, Serth Katrin, Rachev Ev, Alten Leonie, Kremmer Elisabeth, Ueffing Marius, Blum Martin, Gossler Achim, ;2020;Development (Cambridge, England);147;; 32376681