MGI phenotypes (gene matching)
STOCK Ptk2btm1.2Geno/Orl
| Status | Available to order |
| EMMA ID | EM:12902 |
| Citation information | RRID:IMSR_EM:12902 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Ptk2btm1.2Geno/Orl |
| Alternative name | Ptk2b fl/fl |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Ptk2btm1.2Geno |
| Gene/Transgene symbol | Ptk2b |
Information from provider
| Provider | Jean-Antoine Girault |
| Provider affiliation | Institut du Fer à Moulin, U1270, Inserm |
| Genetic information | Flanking with loxP sequences of exons 15b-18, coding for the kinase domain in C57BL/6. |
| Phenotypic information | Homozygous:Mutant mice breed and develop normally.Heterozygous:No alteration. |
| Breeding history | Bred at Charles River and then CNRS TAAM CDTA. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | homozygous C57BL/6 males |
Disease and phenotype information
Literature references
- Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.;Giralt Albert, Brito Veronica, Chevy Quentin, Simonnet Clémence, Otsu Yo, Cifuentes-Díaz Carmen, de Pins Benoit, Coura Renata, Alberch Jordi, Ginés Sílvia, Poncer Jean-Christophe, Girault Jean-Antoine, ;2017;Nature communications;8;15592; 28555636