B6;129-Hint3tm1Jfdr/Orl
| Status | Available to order |
| EMMA ID | EM:13166 |
| Citation information | RRID:IMSR_EM:13166 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Hint3tm1Jfdr/Orl |
| Alternative name | Hint3 cond. KO |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Hint3tm1Jfdr |
| Gene/Transgene symbol | Hint3 |
Information from provider
| Provider | Jean-François Dufour |
| Provider affiliation | DBMR Hepatology, University of Bern |
| Genetic information | Floxed Hint3 gene (129/Sv ES cell line, Genoway France). Deletion of exon 1 upon cre recombinase-mediated excision. |
| Phenotypic information | Homozygous:No evident phenotype during the breeding. These mice were not kept in breeding for a long time as the research project was not initiated.Heterozygous:No evident phenotype during the breeding. These mice were not kept in breeding for a long time as the research project was not initiated. |
| Breeding history | Homozygous and heterozygous animals are fertile and healthy. Maintained genetic background: C57BL/6. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Literature references
- The histidine triad protein Hint is not required for murine development or Cdk7 function.;Korsisaari Nina, Rossi Derrick J, Luukko Keijo, Huebner Kay, Henkemeyer Mark, Mäkelä Tomi P, ;2003;Molecular and cellular biology;23;3929-35; 12748294
- Evidence that human histidine triad nucleotide binding protein 3 (Hint3) is a distinct branch of the histidine triad (HIT) superfamily.;Chou Tsui-Fen, Cheng Jilin, Tikh Ilya B, Wagner Carston R, ;2007;Journal of molecular biology;373;978-89; 17870088