C57BL/6-Tg(Myh6-CD63NanoLuc)/Kctt
| Status | Available to order |
| EMMA ID | EM:13202 |
| Citation information | RRID:IMSR_EM:13202 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6-Tg(Myh6-CD63NanoLuc)/Kctt |
| Alternative name | TG-αMHC-STOP-CD63NanoLuc C57BL/6J |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Myh6-Cd63-Nanoluc)# |
| Gene/Transgene symbol | Tg(Myh6-Cd63-Nanoluc)# |
Information from provider
| Provider | Jiang Chang |
| Provider affiliation | Institute of Biosciences and Technology (IBT), Texas A&M University |
| Genetic information | In order to achieve a controllable exosome tagging, a dSTOP sequence flanked by two loxP sites was introduced upstream of CD63NanoLuc reporter, and the expression cassette was driven by cardiomyocyte-specific α-MHC promoter. Linearized DNA containing αMHC-STOP-CD63NanoLuc cassette was used for pronuclear microinjection to generate the founder of the transgenic strain. |
| Phenotypic information | Homozygous:N/AHeterozygous:Mice are fertile and viable without obvious abnormality. |
| Breeding history | This transgenic strain is bred with C57BL/6J for 6 generations. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Literature references
- Spatial and temporal tracking of cardiac exosomes in mouse using a nano-luciferase-CD63 fusion protein.;Luo Weijia, Dai Yuan, Chen Zhishi, Yue Xiaojing, Andrade-Powell Kelsey C, Chang Jiang, ;2020;Communications biology;3;114; 32157172