B6.129P2(C)-Ring1tm1Mvi/Cnbc
| Status | Available to order |
| EMMA ID | EM:13228 |
| Citation information | RRID:IMSR_EM:13228 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129P2(C)-Ring1tm1Mvi/Cnbc |
| Alternative name | Ring1tm1Mvi |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Ring1tm1Mvi |
| Gene/Transgene symbol | Ring1 |
Information from provider
| Provider | Miguel Vidal |
| Provider affiliation | Centro de Investigaciones Biológicas Margarita Salas |
| Genetic information | Null allele resulting from deletion of most coding sequences |
| Phenotypic information | Homozygous:Adult animals without obvious phenotype observable. Skeletal defects seen during embryonic development.Heterozygous:No observable phenotype |
| Breeding history | Backcrossed at least 6-7 times onto C57BL/6 |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6J males |
Literature references
- Loss- and gain-of-function mutations show a polycomb group function for Ring1A in mice.;del Mar Lorente M, Marcos-Gutiérrez C, Pérez C, Schoorlemmer J, Ramírez A, Magin T, Vidal M, ;2000;Development (Cambridge, England);127;5093-100; 11060235