IMPC phenotypes (gene matching)
- hyperplasia / IMPC
129-Trex1tm2.1Fwpe/H
| Status | Available to order |
| EMMA ID | EM:13234 |
| Citation information | RRID:IMSR_EM:13234 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | 129-Trex1tm2.1Fwpe/H |
| Alternative name | Trex1 R114H |
| Strain type | Targeted Mutant Strains : Point mutation |
| Allele/Transgene symbol | Trex1tm2.1Fwpe |
| Gene/Transgene symbol | Trex1 |
Information from provider
| Provider | Fred W. Perrino |
| Provider affiliation | Ximbio |
| Genetic information | Mutant mice were generated on a 129S6/SvEvTac background using an allelic replacement strategy. |
| Phenotypic information | Homozygous:UnknownHeterozygous:No phenotypic differences were observed. |
| Breeding history | Intercrossing of R114H mice with wild-type mice yielded the expected Mendelian ratios, moreover, R114H male and female mice are fertile and no defects in any organs studied have been observed. Animals are reproductively mature at 6-8 weeks of age and a decline in reproductive performance can be observed from 8 months of age. Average length of gestation is 20 days and the average litter size is 6 pups, of which all would be expected to survive to weaning. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |