STOCK A Mc1re Tg(MC1R)1Jkn/H[cc]
| Status | Available to order |
| EMMA ID | EM:13310 |
| Citation information | RRID:IMSR_EM:13310 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK A Mc1re Tg(MC1R)1Jkn/H[cc] |
| Alternative name | Tg(MC1R)1Jkn |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(MC1R)1Jkn |
| Gene/Transgene symbol | Tg(MC1R)1Jkn |
Information from provider
| Provider | Ian Jackson |
| Provider affiliation | MRC Human Genetics Unit, University of Edinburgh |
| Genetic information | Human BAC transgene, RPCI11-566K11, containing 146 kb human DNA including the human MC1R gene. |
| Phenotypic information | Homozygous:Mice are indistinguishable from agouti.Heterozygous:Hemizygous mice are slightly lighter than homozygotes. |
| Breeding history | Closed colony; mixed background stock, including A allele at the agouti locus and e (recessive yellow) allele at the Mc1r locus. Maintained as homozygous for the transgene, with occasional outcross to background stock and intercross to generate homozygotes. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | yes |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Humanized MC1R transgenic mice reveal human specific receptor function.;Jackson Ian J, Budd Peter S, Keighren Margaret, McKie Lisa, ;2007;Human molecular genetics;16;2341-8; 17652101